D.O.P (Dioctyl phthalat)
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Other names
Di-sec octyl phthalate
DEHP
Octyl phthalate
Theo trích dẫn trên wikipedia.org.
https://en.wikipedia.org/wiki/Bis(2-ethylhexyl)_phthalate
Other health effects[edit]
Studies in mice have shown other adverse health effects due to DEHP exposure. Ingestion of 0.01% DEHP caused damage to the blood-testis barrier as well as induction of experimental autoimmune orchitis.[29] There is also a correlation between DEHP plasma levels in women and endometriosis.[30]
DEHP is also a possible cancer causing agent in humans, although human studies remain inconclusive, due to the exposure of multiple elements and limited research. In vitro and rodent studies indicate that DEHP is involved in many molecular events, including increased cell proliferation, decreased apoptosis, oxidative damage, and selective clonal expansion of the initiated cells; all of which take place in multiple sites of the human body.[31]
